
Manning had a single level anterior fusion in his neck after undergoing tests and consulting with doctors earlier this week.
The Colts will keep the four-time league MVP on the active roster for now.
For Manning, it is the third surgery in 19 months. He had not fully recovered from a May 23 procedure to fix a damaged nerve in his neck.
Manning had already been ruled out of Sunday's season opener at Houston, ending a streak of 227 consecutive starts including playoffs -- the league's second-longest for a quarterback behind Brett Favre.